Advanced analytical testing & contract research
Advanced Polymer & Small-Molecule Analytical Testing
We help R&D and regulated-product teams solve complex questions involving molecular weight, structure, degradation, thermal behaviour, materials and small-molecule analysis.
Detector architecture
-
01
Sample
Dissolved polymer
-
02
Column
Size separation
-
03
RI
Concentration
-
04
UV
Chromophores
-
05
Viscometer
Intrinsic viscosity
-
06
MALS
Absolute Mw, Rg
Detector combination is selected per material. Not every configuration is required for every question.
Location
London, Ontario, Canada
Chromatography
12+ GPC Systems
Detection
Multi-Detector SEC/GPC
Mass spectrometry
LC-MS Expertise
Team
Multidisciplinary Scientists
The problem
Complex analytical questions require more than an instrument.
Advanced products rarely resolve with a single measurement. The result depends on the analytical method, the detectors used, the sample preparation strategy and whether complementary techniques were applied.
PolyAnalytik scientists help determine what needs to be measured, which analytical approach is appropriate, how the analysis should be performed, and what the results actually indicate about your material or product.
Core expertise
Three areas where our science is deepest
01
Polymer Characterization
Molecular weight, molecular-weight distribution, branching, thermal behaviour, degradation, structure and material performance.
02
Small-Molecule & LC-MS Analysis
Quantitative and qualitative analysis supporting pharmaceutical, medical-device and research programs.
03
Analytical Development & Contract Research
Method development, method validation and multidisciplinary analytical support for complex programs.
Core expertise
Advanced GPC/SEC for complex polymer questions
Multiple chromatographic configurations, including multi-detector systems, allow molecular weight to be measured absolutely rather than inferred from calibration standards alone.
- Conventional GPC/SEC
- Light Scattering / MALS
- Viscometry
- Triple Detection
- Molecular Weight Distribution
- Intrinsic Viscosity
- Radius of Gyration
- Polymer Branching
- Polymer Degradation
- Multi-Detector Analysis
Detector architecture
-
01
Sample
Dissolved polymer
-
02
Column
Size separation
-
03
RI
Concentration
-
04
UV
Chromophores
-
05
Viscometer
Intrinsic viscosity
-
06
MALS
Absolute Mw, Rg
Detector combination is selected per material. Not every configuration is required for every question.
Industries
Scientific expertise across complex product environments
Problem-based navigation
What are you trying to understand?
Enter through the scientific question rather than the instrument. Each question leads to the applicable analytical approach.
Techniques
Analytical techniques, and what each one answers
GPC / SEC
Molecular weight, molecular weight distribution, branching and solution size.
DSC
Thermal transitions, Tg, melting and crystallization.
LC-MS
Identification and quantitation of small molecules in complex matrices.
NMR
Molecular structure, composition and copolymer ratios.
FTIR
Chemical functional groups, identification and oxidation.
TGA
Thermal stability, filler content and volatile loss.
DLS
Particle and molecular size distribution in solution.
XRD
Crystalline phase, structure and crystallinity.
SEM / EDX
Surface morphology, fracture features and elemental composition.
XPS
Surface chemistry and elemental oxidation states.
Viscometry
Intrinsic viscosity and solution behaviour.
How a project works
From question to decision-ready results
Step 1
Define the Question
Tell us what you need to understand — the material, the observation and the decision it supports.
Step 2
Design the Analytical Approach
A scientist reviews your samples, objective and the methods appropriate to the question.
Step 3
Analyze & Interpret
Testing is performed using suitable analytical techniques, with interpretation alongside the data.
Step 4
Deliver Decision-Ready Results
Structured data, clear reporting and scientific support for what the results mean.
Scientific authority
Scientific expertise behind every method
[Scientist name to be confirmed]
Ph.D., Polymer Chemistry
Lead Scientist, Polymer Characterization
Multi-detector SEC, branching analysis and degradation mechanisms in resorbable and engineering polymers.
GPC / SEC
Viscometry
DSC
[Scientist name to be confirmed]
Ph.D., Analytical Chemistry
Lead Scientist, Mass Spectrometry
LC-MS method development and quantitation in complex matrices, including release and extraction studies.
LC-MS
NMR
[Scientist name to be confirmed]
Ph.D., Materials Science
Senior Scientist, Thermal & Materials Characterization
Thermal analysis, morphology and failure investigation across polymers, composites and devices.
DSC
TGA
SEM / EDX
[Scientist name to be confirmed]
M.Sc., Chemistry
Quality & Method Validation Lead
Method validation, data integrity and documentation for regulated programs.
LC-MS
GPC / SEC
Scientific resources
Technical resources for complex analytical decisions
Technical Guide
Absolute vs Relative Molecular Weight
Two laboratories can report different molecular weights for the same polymer and both be correct. Understanding the difference between calibrated and absolute measurement prevents avoidable specification disputes.
7 min read
Application Note
How Polymer Processing Can Change Molecular Weight
Extrusion, moulding, drying and regrind all impose thermal and mechanical history. This note describes where chain scission typically originates and how to design a study that isolates it.
6 min read
Regulatory Guide
Analytical Method Validation Under ICH Q2(R2)
An orientation to the performance characteristics relevant to analytical procedure validation, and how the intended use of a method shapes the protocol.
11 min read
Case Study
Case Study: Investigating Molecular Weight Loss After Sterilization
An illustrative investigation in which a resorbable polymer component showed unexpected mechanical change after gamma irradiation. Data shown is illustrative and does not represent a specific client program.
8 min read
Start a project
Not sure which analytical method your project requires?
Describe your samples, objective, material or technical challenge. A PolyAnalytik scientist can help determine the appropriate next step.